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Osteoporosis

Northumberland osteoporosis guidelines

Osteoporosis risk factor scoring


General

Risk of fracture increases by 2-3 if bone density more than 1sd from mean. 10% of women and 50% of men have a secondary cause.

 Bone mass

Risk factors for bone loss

Secondary causes of osteoporosis

Protection

Adequate calcium intake is 800mg/day (1500mg/day post menopausal) but most adults only achieve 500mg/day. Calcium supplementation amy be useful when dietary intake is low and physical activity high. It is not a substitute for HRT postmenopausally, but may have a small place in the prevention of hip (not vertebral) fractures. Chewable or effervescent tabs give most reliable absorption. 2 pints of milk contain 1500mg calcium.

Pointers

Identification

Relative risk of skeletal sites can be predicted: 1sd decrease in bone mineral density increases

Interpreting DEXA Results

DXA results are reported as T scores (comparison with the young adult mean) and Z scores (comparison with reference values of the same age). The T score relates to absolute fracture risk whereas the Z score related to the individual’s relative risk for their age. The table below shows a simple classification of DXA results and guidance for management:

T score (WHO standard reference) Fracture Risk Action
Normal T > -1.0 Low Lifestyle advice
Low bone mass (osteopenia) T –1.0 to –2.5 Above average Lifestyle advice. HRT especially in women aged 50 – 60 years. Calcium and vitamin D supplementation.
Osteoporosis T< -2.5
Treat 
High Lifestyle advice Calcium and vitamin D supplementation
Established osteoporosis T < -2.5 plus one or more fractures Very high Lifestyle advice. Pain control. Exclude secondary causes. Treat (see below). Calcium and vitamin D supplementation. Consider referral.
 

WHO classification of osteoporosis

  Bone mineral density* T score Prevalence (%){dagger}
Normal <1 SD >–1 20
Osteopenia (or low bone mass) 1-2.5 SD –1 to –2.5 52
Osteoporosis ≥2.5 SD ≤–2.5 28

*Below the young adult mean.

{dagger}In white women older than 50 years.