Fever

Source: BMJ

Early "red flags" for meningococcal disease

Excluding serious illness in feverish children in primary care: restricted rule-out method for diagnosis

 

Symptoms and signs of bacterial meningitis and meningococcal septicaemia
Symptom or sign Bacterial meningitis (meningococcal meningitis and meningitis caused by other bacteria) Meningococcal disease (meningococcal meningitis, meningococcal septicaemia, or both) Meningococcal septicaemia
Common non-specific symptoms or signs
Fever (not always present, especially in neonates) Yes Yes Yes
Vomiting or nausea Yes Yes Yes
Lethargy Yes Yes Yes
Irritable or unsettled Yes Yes Yes
Look ill Yes Yes Yes
Refusing food or drink Yes Yes Yes
Headache Yes Yes Yes
Muscle ache or joint pain Yes Yes Yes
Respiratory symptoms or signs or breathing difficulty Yes Yes Yes
Less common non-specific symptoms or signs
Chills or shivering Yes Yes Yes
Diarrhoea, abdominal pain, or distension Yes Yes NK
Sore throat or coryza or other ear, nose, and throat symptoms or signs Yes Yes NK
More specific symptoms or signs
Non-blanching rash (may be less visible in darker skin tones—check soles of feet, palms of hands, and conjunctivas) Yes Yes Yes
Stiff neck Yes Yes NK
Altered mental state (includes confusion, delirium, drowsiness, and impaired consciousness) Yes Yes Yes
Capillary refill time more than 2 seconds NK Yes Yes
Unusual skin colour NK Yes Yes
Shock Yes Yes Yes
Hypotension NK Yes Yes
Leg pain NK Yes Yes
Cold hands or feet NK Yes Yes
Back rigidity Yes Yes NK
Bulging fontanelle (only relevant in children under 2 years) Yes Yes NK
Photophobia Yes Yes X
Kernig’s sign* Yes Yes X
Brudzinski’s sign{dagger} Yes Yes X
Unconsciousness Yes Yes Yes
Toxic or moribund state Yes Yes Yes
Paresis Yes Yes X
Focal neurological deficit including cranial nerve involvement and abnormal pupils Yes Yes X
Seizures Yes Yes X

*With the patient lying flat on his or her back, inability to extend the knees beyond 135° without causing pain; {dagger}with the patient supine, one hand placed behind the patient’s head and the other hand on the patient’s chest, while the patient’s head is raised, flexion of the patient’s lower extremities (hips and knees) constitutes a positive sign.

Yes=symptom or sign present; X=symptom or sign not present; NK not known if a symptom or sign is present (not reported in the evidence).

Management of bacterial meningitis and meningococcal septicaemia in children and young people: summary of NICE guidance

 

Normal heart and respiratory rates at rest by age


Age (years) Heart rate (beats per minute) Respiratory rate (breaths per minute)
<1 110-160 30-40
1-2 100-150 25-35
2-5 95-140 25-30
5-12 80-120 20-25
12 60-100 15-20

From: Advanced Life Support Group. Advanced Paediatric Life Support: The Practical Approach. 4th ed. Wiley Blackwell, 2004.

 

Urinary tract infection

Suspicion should always result in urine culture and microscopy (this is more important than treatment!). If significant bacteriuria and age under 5:

Urinary tract infection (UTI) in children

Note: NICE guidelines have been published in late 2007 which potentially simplify UTI management in children. There is still much professional debate about  these guidelines, however.

Measles

Rubella

Roseola infantum

Chickenpox

Scarlet fever

Herpetic infections

Mumps