Occurs in 12-15% of middle ages population but only 1/3 seek advice.

  1. Change in bowel habit
    • Change in bowel habit implies a structural narrowing and barium enema is a sensitive investigation except for the rectosigmoid and areas of severe diverticular disease
    • If age >40 and persisting for >1 month needs investigation
    • Refer for surgical opinion.
  2. Rectal bleeding
    • All patients with rectal bleeding aged over 40 should be investigated
    • Possible investigation strategies
      • Rectal examination - if palpable tumour - urgent surgical clinic referral
      • Open access flexible sigmoidoscopy
    • Barium enema is not an adequate investigation of rectal bleeding since it does not reliably identify significant polyps

Patterns of bleeding, possible causes and suggested urgencies

See colorectal problems for urgency classification

Type of Blood Associated Features Possible Causes Suggest Referral to
Bright red on toilet paper
painful
throbs for hours
fissure in ano surgical OPD
before motion or with motion polyp or cancer Open Access Flexible Sigmoidoscopy
after motion
drips into toilet
haemorrhoids Open Access Flexible Sigmoidoscopy
Dark red   cancer or polyp Open Access Flexible Sigmoidoscopy
Any colour passed alone cancer or polyp Open Access Flexible Sigmoidoscopy
  1. Anaemia
    • If hypochromic microcytic, gastric or colonic malignancy should be excluded
    • Faecal Occult Bloods are not useful since they have a 20% false negative for colorectal cancer and a 70% false negative rate for colomc polyps
    • Possible investigation strategies are
      • surgical or medical referral
      • open access gastroscopy, if negative surgical/medical referral for colonoscopy
  2. Abdominal pain
    • surgical referral if clinically concerned
  3. Family history of colorectal cancer
    • If symptomatic, refer
    • If asymptomatic screening can be offered on the basis of assessed risk
    • High risk groups are 1st degree relatives of patients aged <45 with colorectal cancer and those families with multiple cancers.
  4. Squamous carcinoma of the anus
    • A non healing ulcer of the anal verge should be urgently referred

Staging in colorectal cancer vs 5-year survival

Stage 5-year survival
A 95%
B1 85%
B2 60%
C1 55%
C2 30%
D 0%