Urgent '2 week rule'

Pts at high risk colorectal cancer
  • Aged more than 50 and 
    • Rectal bleeding and change in bowel habit for more than 6 weeks 
    • Rectal bleeding without anal symptoms ( Loose stools for more than 6 weeks 
    • Anaemia, iron deficient, Hb less than 10 
    • Obvious abdominal or rectal mass 
Soon
  • Patients aged less than 50 with high risk symptoms as before or... 
  • Low risk symptoms
    • Rectal bleeding and change in bowel habit for less than 6 weeks 
    • Rectal bleeding and anal symptoms 
    • Constipation (decreased frequency, increased hardness) 
    • Abdominal pain 
    • Prolonged history of recurrent symptoms 
Routine
  • Anal canal symptoms 
  • Incontinence 
  • Prolapse 
  • Family history: 
    3 relatives with colorectal cancer or 2 relatives with colorectal cancer and 1 relative with endometrial, gastric, uro-epithelial or small intestine cancer (1 first degree relative. 1 under 50 and at least 2 generations affected)

Information to patient

Referral information required

Referral priority Urgent/soon/routine
Index suspicion of cancer Definitely not ................ definitely cancer
Colorectal symptoms
  • Duration of symptoms
  • Rectal bleeding
  • Change in bowel habit
  • Anal symptoms
  • Rectal mass
  • Incontinence
  • Abdominal pain

Relative risks

Pedigree Lifetime risk of colorectal cancer
Population risk 1 in 30
1 first degree relative 1 in 17
1 first degree and 1 second degree relative 1 in 12
1 first degree relative aged <45 1 in 10
2 first degree relatives 1 in 6

Duke's classification

Extent of disease Duke's stage Cure rate
Confined to bowel wall A 90%
Penetrating bowel wall B 70%
Involving lymph nodes C 30%
Distant metastases D <5%