- The first priority is to control heart rate (if tachycardia is
present) and provide adequate antithrombotic treatment for
preventing complications of embolism
- Patients with moderate to high risk of stroke require warfarin
long term for preventing emboli; aspirin is adequate in patients
with low risk of stroke
- When a patient should but cannot take warfarin, aspirin plus
clopidogrel can be an intermediate option
- For long term treatment of atrial fibrillation, rate control
matches rhythm control in terms of mortality and major
cardiovascular events but has fewer adverse events related to the
treatment and fewer hospital admissions
- Consider referring for rhythm control younger patients with lone
atrial fibrillation, patients with symptomatic atrial fibrillation,
and patients with atrial fibrillation secondary to a corrected
precipitant
- If antiarrhythmic drugs fail to maintain sinus rhythm,
percutaneous catheter ablation is an alternative for rhythm control
If patient stable and on warfarin - do not interfere.
- If atrial fibrillation present for more than one year,
cardioversion usually not done.
- If atrial fibrillation present for less than one year, consider
cardioversion.
- If atrial fibrillation uncontrolled, use digoxin.
- What is cause of atrial fibrillation?
- ECG
- CXR
- TFT
(U&E, FBC, LFT)
- Echocardiography
determines whether patient should be commenced on aspirin or
warfarin.
Treatment
- Patients with tachycardia plus syncope, chest pain,
dyspnoea, or acute neurological symptoms should be sent
immediately to hospital for urgent treatment
- Use β blockers, diltiazem, or digoxin (if heart
failure is present), or a combination of these drugs at
standard doses to slow heart rate in atrial fibrillation
if tachycardia is present
|
BHF factfiles
NICE CG36
CKS on AF |
NICE atrial fibrillation guidelines
10-Minute
Consultation: atrial fibrillation
Atrial fibrillation emergency resuscitation
Management of atrial fibrillation BMJ 2009
Starting digoxin
Loading dose
15mcg per kg of estimated lean body weight, given in 3 divided doses at 6
hour intervals
eg: 50kg woman requires 750mcg = 250mcg x3 doses 6 hours apart.
If ventricular rate not slowed and no signs of toxicity, try another 5mcg
per kg
Maintenance
| Creatinine clearance (ml/min) |
Daily maintenance dose as a fraction of
effective loading dose |
| 100 |
1/3 |
| 50 |
1/4 |
| 25 |
1/5 |
| 10 |
1/6 |
| 0 |
1/7 |
Reference: BHF factfile 7/2001