It is recommended that these symptom and sign combinations when occurring for the first time should be used to identify patients for urgent referral under the two week standard:

All Ages

Over 60 years

  • Rectal bleeding persistently WITHOUT anal symptoms*
  • Change of bowel habit to looser stools and/or increased frequency of defecation, WITHOUT rectal bleeding and persistent for six weeks.

Age 60 years is considered to be the maximum age threshold. Local Cancer Networks may elect to set a lower age threshold (eg 55 years or 50 years)

Any Age

  • Iron deficiency anaemia WITHOUT an obvious cause (Hb < 11 g/dl in men or < 10 g/dl in postmenopausal women).

NB. Patients with the following symptoms and no abdominal or rectal mass, are at very low risk of cancer:

  • Rectal bleeding with anal symptoms*
  • Change in bowel habit to decreased frequency of defaecation and harder stools.
  • Abdominal pain without clear evidence of intestinal obstruction.

* Anal symptoms include soreness, discomfort, itching, lumps and prolapse as well as pain.


Source: Department of Health urgent referral guidelines