HRT risk is  a developing story, confounded by different

Breast cancer risk - calculated variations in absolute risk based on metadata analysis

Age at calculation % risk with no HRT 3 years combination HRT 5 years combination HRT 10 years combination HRT 15 years combination HRT 3 years oestrogen only HRT 5 years oestrogen only HRT 10 years oestrogen only HRT 15 years oestrogen only HRT
40 7.21 7.39 7.59 8.39 9.43 7.26 7.33 7.55 7.85
45 6.76 7.02 7.28 8.21 9.3 6.83 6.91 7.17 7.49
50 6.1 6.41 6.7 7.69 8.92 6.19 6.28 6.55 6.91
55 5.3 5.63 5.94 7.06 8.47 5.39 5.49 5.8 6.21
60 4.44 4.81 5.17 6.45 7.95 4.54 4.65 5.01 5.44
65 3.48 3.9 4.32 5.67 6.75 3.6 3.73 4.1 4.39
70 2.37 2.84 3.25 4.21   2.5 2.62 2.87  
75 1.14 1.57 1.72     1.26 1.28    

Hormone replacement therapy and breast cancer: estimate of risk (2005)

Hormone therapy for menopausal symptoms (2012): the increased risk of breast cancer associated with use of combined oestrogen-progestogen (hazard ratio 1.24) is similar to risks conferred by delayed menopause or moderate use of alcohol.

 

Estimated benefits and risks of oral HRT in postmenopausal women aged 50-59 years, or <10 years after menopause (2012)

Hormone replacement therapy (2012)